Effect of Positive Airway Pressure Treatment on the Quality-of-Life of Patients with Sleep Apnoea Syndrome

Kemal Kiraz, Mustafa Çörtük, Burcak Zitouni, Erdem Atalay Çetinkaya, Ali Ramazan Benli
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Objectives: Sleep apnoea syndrome (OSA) is closely associated with obesity and cardiovascular diseases. OSA disrupts neurocognitive functioning and negatively affects quality of life. Use of a positive airway pressure (PAP) device remains the gold standard treatment for OSA. We used the Short Form-36 (SF-36) instrument to measure quality-of-life changes in PAP-treated patients in Turkey.

Materials and Methods: The present study included 67 (52 male) consecutive OSA patients treated with a PAP device. Each subject underwent overnight full-laboratory polysomnographic examination. The SF-36 scores of patients given a PAP device were measured before they commenced using the device and 6–18 months later.  

Results: Appropriate use of PAP devices improved quality of life as evidenced by improvement on all parameters of the SF-36 instrument quality-of-life scale (P<0.05).

Conclusion: We found that PAP therapy significantly improved quality of life. This study is the first in Turkey to use the SF-36.


Sleep Apnea Syndrome, continuous positive airway pressure, quality of life, Short form 36

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Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 1993;328(17):1230-5.

Somers VK, Dyken ME, Clary MP, Abboud FM. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest 1995;96(4):1897-904.

Shafazand S. Perioperative management of obstructive sleep apnea: ready for prime time? Cleve Clin J Med 2009;76:4:98-103.

Somers VK, White DP, Amin R, et al. Sleep apnea and cardiovascular disease: an American Heart Association/American College of Cardiology Foundation Scientific Statement from the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing. J Am Coll Cardiol 2008;52(8):686-717.

Bradley TD, Floras JS. Obstructive sleep apnoea and its cardiovascular consequences. The Lancet 2009;373(9657):82-93.

Flemons WW, Tsai W. Quality of life consequences of sleep-disordered breathing. J Allergy Clin Immunol 1997;99(2):750-6.

Baldwin CM, Griffith KA, Nieto FJ, O'Connor GT, Walsleben JA, Redline S. The association of sleep-disordered breathing and sleep symptoms with quality of life in the Sleep Heart Health Study. Sleep 2001;24(1):96-105.

Karkoulias K, Lykouras D, Sampsonas F, et al. The impact of obstructive sleep apnea syndrome severity on physical performance and mental health. The use of SF-36 questionnaire in sleep apnea. Eur Rev Med Pharmacol Sci 2013;17(4):531-6.

Ware JE, Jr., Sherbourne CD. The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Med Care 1992;30(6):473-83.

Kocyigit H, Aydemir O, Fisek G, Olmez N, Memis A. Validity and reliability of Turkish version of Short form 36: A study of a patients with romatoid disorder. J Drug Ther 1999;12:102-6.

Yurtlu S, Sariman N, Levent E, Soylu AC, Alparslan S, Saygi A. Short-term positive airway pressure therapy response in obstructive sleep apnea patients: impact of treatment on the quality of life. Tuberk toraks 2012;60(4):327-35.

Siccoli MM, Pepperell JC, Kohler M, Craig SE, Davies RJ, Stradling JR. Effects of continuous positive airway pressure on quality of life in patients with moderate to severe obstructive sleep apnea: data from a randomized controlled trial. Sleep 2008;31(11):1551-8.

Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 1991;14(6):540-5.

Iber C, Ancoli-Israel S, Chesson AL, Quan SF. The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications. Westchester, IL: American Academy of Sleep Medicine; 2007.

Loube DI, Gay PC, Strohl KP, Pack AI, White DP, Collop NA. Indications for positive airway pressure treatment of adult obstructive sleep apnea patients: a consensus statement. Chest 1999;115(3):863-6.

Fidan F, Unlu M, Sezer M, Gecici O, Kara Z. Compliance to CPAP treatment and effects of treatment on anxiety and depression in patients with obstructive sleep apnea syndrome. Tuberk toraks 2007;55(3):271-7.

Campos-Rodriguez F, Pena-Grinan N, Reyes-Nunez N, et al. Mortality in obstructive sleep apnea-hypopnea patients treated with positive airway pressure. Chest 2005;128(2):624-33.

Wozniak DR, Lasserson TJ, Smith I. Educational, supportive and behavioural interventions to improve usage of continuous positive airway pressure machines in adults with obstructive sleep apnoea. Cochrane Database Syst Rev 2014;1:CD007736.

Andrade RG, Piccin VS, Nascimento JA, Viana FM, Genta PR, Lorenzi-Filho G. Impact of the type of mask on the effectiveness of and adherence to continuous positive airway pressure treatment for obstructive sleep apnea. J Bras Pneumol 2014;40(6):658-68.

Koyuncu T. Günay E US, Akar O, Ulu Ş, Ünlü M. The Impact of Continuous Positive Airway Pressure (CPAP) Training on the Compliance of Device Usage and Quality of Life in Patients with Obstructive Sleep Apnea Syndrome. Solunum Hastalıkları 2013;24:58-63.

Massie CA, Hart RW, Peralez K, Richards GN. Effects of humidification on nasal symptoms and compliance in sleep apnea patients using continuous positive airway pressure. Chest 1999;116(2):403-8.

Antic NA, Catcheside P, Buchan C, et al. The effect of CPAP in normalizing daytime sleepiness, quality of life, and neurocognitive function in patients with moderate to severe OSA. Sleep 2011;34(1):111-9.

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