Yıl 2018, Cilt 18, Sayı 4, Sayfalar 528 - 536 2018-12-27

Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc?
Astımlı Çocukların Serum D Vitamini ve Çinko Düzeyleri ile Klinik Bulguları Arasında Bir İlişki Var mı?

Zehra Şule Haskoloğlu [1] , Demet Altun [2]

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Objectives: It is reported that deficiencies in vitamin D and zinc are associated with asthma. In this study we aimed to investigate the relationship between clinic findings of asthmatic children and vitamin D and zinc levels.
Materials and Methods: This prospective study included a total of 149 asthmatics and 97 healthy children with an age range of 5 to 17 years. All of the participants were evaluated for serum levels of 25 -hydroxyvitamin D (25(OH)D) and zinc, dietary habits, the rate of respiratory tract infections, hospital visits and levels of sunlight exposure.
Results: Serum vitamin D and zinc levels in asthmatic children (7.7±5.29 ng/ml), (64±16.3 mcg/dl) were significantly lower than that in healthy children (12.3±12.87 ng/ml), (69±26.2 mcg/dl) (p< 0.015), respectively. A relationship was detected between the frequency of infection and vitamin D level’s being <10ng/ml (p < 0.001), while no relationship was detected between the frequency of infection and zinc level. No relationship was detected between pulmonary function, nutrition and the levels of vitamin D and zinc. However, a relationship was detected between vitamin D levels and exposure to sunlight.
Conclusion: Our results showed that asthmatic children had lower vitamin D and zinc levels than healthy children. Very low levels of vitamin D were found to be associated with an increased rate of infection and required more medication and hospitalization

Amaç: Vitamin D ve çinko eksikliğinin astım ile ilişkili olduğu bildirilmektedir. Bu çalışmada astımlı

çocukların klinik bulguları ile vitamin D ve çinko düzeyleri arasındaki ilişkiyi araştırmayı istedik.

Materyal ve Metot: Bu prospektif çalışmaya yaşları 5‐17 arasında değişen 149 astımlı ve 97 sağlıklı çocuk

dahil edildi. Tüm katılımcıların serum 25 hidroksivitamin D (25(OH)D) ve çinko düzeyleri ölçüldü, diyet

alışkanlıkları, bir yıldaki solunum yolu enfeksiyonu sıklıkları, hastane başvuruları ve güneş ışığına

maruziyet süreleri sorgulandı.

Bulgular: Astımlı çocukların serum D vitamini ve çinko düzeyleri sırasıyla (7,7±5,29 ng/ml), (64±16,3

mcg/dl) sağlıklı çocuklardan (12,3±12,87 ng/ml), (69±26,2 mcg/dl) belirgin şekilde düşük bulundu (p

<0,001) (p <0,015). Serum D vitamini düzeyinin 10ng/ml'nin altında olması ile enfeksiyon sıklığı arasında

ilişki bulunurken çinko düzeyi ile ilişki saptanmadı. Pulmoner fonksiyonlar, beslenme ile D vitamini

düzeyi arasında ilişki saptanmadı. Ancak güneşe maruziyet ile D vitamini düzeyi arasında bir ilişki

saptandı.

Sonuç: Sonuç: Bizim sonuçlarımız astımlı çocukların sağlıklı çocuklardan daha düşük D vitamini ve

çinko düzeyine sahip olduğunu göstermektedir. D vitamininin çok düşük düzeylerde olması artmış

enfeksiyon riski, daha çok tedavi ihtiyacı ve hastane yatışı ile ilişkili ulundu.

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Konular Sağlık Bilimleri ve Hizmetleri
Dergi Bölümü Araştırmalar
Yazarlar

Yazar: Zehra Şule Haskoloğlu (Sorumlu Yazar)

Yazar: Demet Altun

Bibtex @araştırma makalesi { amj499653, journal = {Ankara Medical Journal}, issn = {}, eissn = {2148-4570}, address = {Ankara Yıldırım Beyazıt Üniversitesi}, year = {2018}, volume = {18}, pages = {528 - 536}, doi = {10.17098/amj.499653}, title = {Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc?}, key = {cite}, author = {Haskoloğlu, Zehra Şule and Altun, Demet} }
APA Haskoloğlu, Z , Altun, D . (2018). Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc?. Ankara Medical Journal, 18 (4), 528-536. DOI: 10.17098/amj.499653
MLA Haskoloğlu, Z , Altun, D . "Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc?". Ankara Medical Journal 18 (2018): 528-536 <http://www.ankaramedicaljournal.com/issue/40944/499653>
Chicago Haskoloğlu, Z , Altun, D . "Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc?". Ankara Medical Journal 18 (2018): 528-536
RIS TY - JOUR T1 - Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc? AU - Zehra Şule Haskoloğlu , Demet Altun Y1 - 2018 PY - 2018 N1 - doi: 10.17098/amj.499653 DO - 10.17098/amj.499653 T2 - Ankara Medical Journal JF - Journal JO - JOR SP - 528 EP - 536 VL - 18 IS - 4 SN - -2148-4570 M3 - doi: 10.17098/amj.499653 UR - http://dx.doi.org/10.17098/amj.499653 Y2 - 2019 ER -
EndNote %0 Ankara Medical Journal Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc? %A Zehra Şule Haskoloğlu , Demet Altun %T Is There a Relationship between Clinical Symptoms of Asthmatic Children and Serum Levels of Vitamin D and Zinc? %D 2018 %J Ankara Medical Journal %P -2148-4570 %V 18 %N 4 %R doi: 10.17098/amj.499653 %U 10.17098/amj.499653
ISNAD Haskoloğlu, Zehra Şule , Altun, Demet . "Astımlı Çocukların Serum D Vitamini ve Çinko Düzeyleri ile Klinik Bulguları Arasında Bir İlişki Var mı?". Ankara Medical Journal 18 / 4 (Aralık 2018): 528-536. http://dx.doi.org/10.17098/amj.499653